Next Gen Immunology 2020 Program

Program

Sunday, February 2
Time	Session/Lecture info
08:30-10:45	Registration
08:30-10:45
10:45-11:30	Welcome and Introduction
10:45-11:30	On behalf of the Weizmann Institute of Science: Alon Chen, President On behalf of the Weizmann Immunology Department: Michael Sela On behalf of Nature: Ursula Weiss (editor, Nature) and Joao Monteiro (editor, Nature Medicine)
11:30-18:00	Session 1: Host-microbe and host-microbiome interactions Chairs: Omry Koren (BIU, Israel); Yehudit Bergman (HUJI, Israel)
11:30-12:10	Margaret McFall-Ngai, U Hawaii, USA Keynote I: The complex molecular dialogue of host-symbiont communication: Initiating and maintaining a stable symbiosis
12:10-13:30	Lunch
13:30-14:00	Eric Pamer, University of Chicago, USA Microbiota-mediated defense against intestinal infection
14:00-14:30	Noah Palm, Yale, USA Illuminating the ’dark matter’ of the bioactive microbiota metabolome
14:30-15:00	Lalita Ramakrishnan, Cambridge, UK Learning immunology from the tubercle bacillus
15:00-15:15	Petter Brodin, Karolinska, Sweden Short talk: Human immune system development during the first weeks and months of life
15:15-15:45	Eran Elinav, Weizmann, Israel Host-Microbiome interactions in health and disease
15:45-16:00	Naama Geva-Zatorsky, Technion, Israel Short talk: Combinatorial gut microbiota-host interactions
16:00-16:30	Refreshment Break
16:30-16:45	Megha Basavappa, Upenn, USA Short talk: Characterizing the role of long noncoding RNAs in innate antiviral responses
16:45-17:15	Rotem Sorek, Weizmann, Israel Evolutionary origin of the cGAS-STING innate immunity pathway in microbial defense against phage
17:15-17:30	Shai Bel, BIU, Israel Short talk: Autophagy and IBD: trickier than expected
17:30-18:00	Richard Flavell, Yale, USA Tales of T cell tails
18:00-19:00	Poster Session 1 & Drinks Reception
18:00-19:00
19:00-21:30	Festive Dinner
19:00-21:30

Monday, February 3
Time	Session/Lecture info
09:00-12:25	Session 2: Cancer immunology Chairs: Klaus Rajewsky (MDC, Germany); Irit-Gat Viks (TAU, Israel)
09:00-09:40	Miriam Merad, MSSM, USA Keynote II: Myeloid determinants of tumor immunity
09:40-09:55	Eric Vivier, CIML/ Innate Pharma, France Short talk: Harnessing innate immunity in cancer therapy
09:55-10:25	Ido Amit, Weizmann, Israel The power of ONE: Immunology in the age of single cell genomics
10:25-10:55	Refreshment Break
10:55-11:10	Zvika Granot, HUJI, Israel Short talk: Neutrophil Specific Targeting as a Novel Mode of Immunotherapy
11:10-11:40	Amos Tanay, Weizmann Institute of Science, Israel Epigenetics and (single) cell fate decisions
11:40-11:55	Shai Shen-Orr, Technion, Israel Short talk: Immune-age - A metric of immune system state
11:55-12:25	Mark Davis, Stanford, USA Analyzing T cell repertoires, functions and specificities in human disease
12:25-13:45	Lunch
12:25-13:45
13:45-16:15	Session 3: Neuro-immunology Chairs: Liran Shlush (Weizmann, Israel); Ari Waisman (U Mainz, Germany)
13:45-14:15	Yinon Ben-Neriah, Hebrew University-Hadassah Medical School, Israel Building on tumor vulnerabilities and harnessing the immune system to fight leukemia
14:15-14:45	Michal Schwarz, Weizmann, Israel Mechanism underlying Immune checkpoint blockade to combat Alzheimer’s disease and Dementia
14:45-15:00	Asya Rolls, Technion, Israel Short talk: Using the brain to control peripheral immunity
15:00-15:30	Elaine Hsiao, UCLA, USA Microbiome-nervous system interactions during early development
15:30-15:45	Daniel Saban, Duke, USA Short talk: A stereotypic subset of microglia that are neuroprotective in etiologically distinct retinal degenerative diseases
15:45-16:15	Refreshment Break
16:15-18:30	Session 4: Adaptive immunity Chairs: Liran Shlush (Weizmann, Israel); Ari Waisman (U Mainz, Germany)
16:15-16:45	Florent Ginhoux, A star, Singapore Macrophage and dendritic cell biology: from development to functions
16:45-17:15	Galit Alter, Harvard, USA Identification of functional humoral correlates and biomarkers of protection using Systems Serology
17:15-17:30	Matteo Iannacone, San Raffaele, Italy Short talk: Spatiotemporal dynamics and genomic landscape of CD8 T cells undergoing intrahepatic priming
17:30-18:00	Sean Bendall, Stanford, USA Single Cell Composition and Structure of Human Immune Metabolism in Health and Disease
18:00-18:30	Rafi Ahmed, Emory, USA Defining T Cell Exhaustion: Implications for Immunotherapy
18:30-19:30	Poster Session 2 & Drinks Reception
18:30-19:30
19:30-21:30	Festive Dinner
19:30-21:30

Tuesday, February 4
Time	Session/Lecture info
09:00-12:55	Session 5: Tissue resident immunity Chairs: Yinon Ben-Neriah (HUJI, Israel), Yifat Merbl (Weizmann, Israel)
09:00-09:40	Akiko Iwasaki, Yale, USA Keynote III: Retroelements in health and disease
09:40-10:10	Shruti Naik, NYU, USA Immune-epithelial crosstalk in tissue regeneration
10:10-10:40	Federica Sallusto, IRB, Switzerland T cell differentiation and plasticity in humans
10:40-11:10	Refreshment Break
11:10-11:40	Carla Rothlin, Yale, USA Phosphatidylserine sensing in life and death
11:40-12:10	Marco Colonna, Wash U, USA Regulation of tissue resident macrophages by the TREM2 immunoreceptor
12:10-12:25	Ziv Shulman, Weizmann, Israel Short talk: Epitranscriptomic regulation of the germinal center reaction
12:25-12:55	Vijay Kuchroo, Harvard, USA Induction and regulation of effector T cell responses in autoimmunity and cancer
12:55-14:15	Lunch
12:55-14:15
14:15-18:15	Session 6: Immunity at the mucosal niche Chairs: Benny Geiger (Weizmann Israel); Dan Peer (TAU, Israel)
14:15-14:45	Thaddeus Stappenbeck, Wash U, USA Integration of immune and microbial factors by the intestinal epithelium
14:45-15:15	Fredrik Backhed, U Gothenburg, Sweden Understanding mechanisms underlying insulin resistance and type 2 diabetes
15:15-15:45	Eran Segal, Weizmann, Israel Personalizing treatments using microbiome and clinical data
15:45-16:30	Refreshment Break
16:30-17:00	Gunnar C. Hansson, U Gothenburg, Sweden Specialized goblet cells secrete and provide different levels of intestinal mucus protection
17:00-17:15	Mark Travis, U Manchester, UK Short talk: Regulation of memory T cells by integrins and TGF-beta
17:15-17:45	Lydia Lynch, Harvard, USA Fueling the firestarters
17:45-18:15	Vishva M. Dixit, Genentech, USA Discovery of a ubiquitin ligase that puts the brake on microglia-mediated inflammation
18:15-23:55	Special Dinner and Party at Ronit Farm (transportation will be provided)
18:15-23:55

Wednesday, February 5
Time	Session/Lecture info
09:00-12:00	Session 7: Immunity to Cancer Chairs: Idit Shachar (Weizmann, Israel); Yardena Samuels (Weizmann, Israel)
09:00-09:30	Alexander Rudensky, Sloan Kettering, USA Transcriptional control of regulatory T cell lineage
09:30-10:00	Dana Pe’er, Sloan Kettering, USA A dynamic view of tumor immune ecosystems
10:00-10:15	Rony Dahan, Weizmann, Israel Short talk: Towards next-generation checkpoint antibodies for cancer immunotherapy
10:15-11:00	Refreshment Break
11:00-11:30	Tom Gajewski, U Chicago, USA Mechanisms of efficacy versus resistance of cancer immunotherapy
11:30-12:00	Ton Schumacher, NKI, Netherlands Dissecting immune reactivity in human cancers using ex vivo avatars
12:00-13:15	Lunch
12:00-13:15
13:15-15:15	Session 8: Harnessing immunity in cancer treatment Chairs: Yossi Yarden (Weizmann, Israel); Dinorah Friedmann-Morvinski (TAU, Israel)
13:15-13:45	Nick Haining, Merck/ Harvard, USA Discovering regulators of the immune response to cancer
13:45-14:15	Ira Mellman, Genentech, USA Mechanistic basis of cancer immunotherapy
14:15-14:30	Neta Erez, TAU, Israel Short talk: Stromal dynamic plasticity shapes the microenvironment in breast cancer metastasis
14:30-15:00	John Wherry, UPenn, USA Genomics, molecular mechanisms and clinical implications of T cell exhaustion
15:00-15:15	Closing Remarks and End of Meeting

Next Gen Immunology 2020 Program

Program

Sunday, February 2