Program (GMT+3)

Israel time zone (GMT+3)

The program will run according to the listed times (in Israel), but participants can view the recorded talks at their convenience following the initial presentation. A live discussion will be held at the end of each session, during which questions and comments can be submitted by chat and will be read out by the moderator. The chat for each talk will remain open for the rest of the meeting, such that the audience and speakers can continue to interact at times convenient for them.

FUNDI2021 Program

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Monday, June 14

Time Session/Lecture info
09:00-09:10
Welcome and introduction
 
09:10-11:30
Session I-- Disulfides in folding, assembly, catalysis, and regulation
 
09:10-09:45
Phil Hogg (plenary), University of Sydney, Australia
Secreted Proteins that are Produced and Function as Multiple Disulfide-bondedor Covalent Forms
09:45-10:00
Chaitan Khosla, Stanford University, USA
An Unusual "OR Gate" for Allosteric Regulation of Mammalian Transglutaminase 2 in the Extracellular Matrix
10:00-10:15
Jan Riemer, University of Cologne, Germany
Redox Processes in Complex I Assembly
10:15-10:30
Weikai Li, Washington University, USA
Structural Mechanisms of Integral Membrane Thiol Oxidoreductases
10:30-10:45
Hiroshi Kadokura, Tohoku University, Japan
Observing the Cotranslational Disulfide Rearrangement in a Cell Surface Multidomain Protein, LDL Receptor, in the ER of Mammalian Cells
10:45-11:30
Discussion
15:00-17:30
Session II-- Disulfides in biophysics, chemical biology, and biotechnology
 
15:00-15:30
Ron Raines (plenary), Massachusetts Institute of Technology, USA
Disulfide Bonds: Quantum Basis for Structure and Function
15:30-15:45
Nir London, Weizmann Institute of Science, Israel
Tunable Methacrylamides for Covalent Ligand Directed Release Chemistry
15:45-16:00
Kai Tittmann, Georg August University, Germany
Redox Switches in Proteins - Beyond Disulfides
16:00-16:15
Mathivanan Chinnaraj, St. Louis University, USA
Sub-millisecond Dynamics Explains Allosteric Modulation of Reduced PDI by Antithrombotic Small Molecule Compounds
16:15-16:30
Niv Papo, Ben Gurion University, Israel
Disulfide Engineering of Kunitz Protease Inhibitors
16:30-16:45
Ruma Banerjee, University of Michigan, USA
A Trisulfide Surprise Involved in Sulfide Oxidation
16:45-17:30
Discussion
19:00-20:00
Networking lounge
 

Registration_button_new

Important deadlines:

Registration deadline: June 1st, 2021

Organizing committee

Deborah Fass
Weizmann Institute of Science

Francisco Rafael Martins Laurindo
University of Sao Paolo

David Essex
Temple University

Sponsors

The Chorafas Institute for
Scientific Exchange

Conference Coordinator

Talia Suissa

talias@weizmann.ac.il