Program

All times in the program are listed as Israel Time

Program – different time zones »
NOTE there may be minor changes in the final program

TT2020 Program

Monday, October 26
Time	Session/Lecture info
15:00-15:15	Opening Address TT2020-Virtual
15:00-15:15
15:15-16:30	Session 1:Panel Discussion - Animal Models: From Bench to Bedside. Sponsored by GEMM - Genetic Engineered Mouse Models; National Israel facility Moderators, Karen Avraham, Jan Parker-Thornburg
15:15-15:30	Paula Rio , CIEMAT, Spain Gene Therapy for Fanconi anemia: From the lab to the clinic
15:30-15:45	Eithan Galun, The Hebrew University of Jerusalem, Israel Better Bedside-to-bench than Bench-to-bedside, why?
15:45-16:00	Aris Economides , Regeneron, USA Inhibition of Activin A by a monoclonal antibody as a disease-modifying therapy for fibrodysplasia ossificans progressiva (FOP)
16:00-16:15	Tom Wishart, Roslin Institute, UK How should we model neurodegenerative conditions? Using livestock to bridge the translational gap.
16:15-16:30	Panel Discussion
16:30-16:45	Break
16:30-16:45
16:45-18:20	Session 2: Epigenetics Chair: Janet Rossant
16:45-17:20	Keynote: HOWARD CEDAR, The Hebrew University of Jerusalem, Israel Remote control of gene expression by DNA methylation
17:20-17:35	Wei Li , Chinese Academy of Sciences, China Balancing embryonic development through ?imbalance?
17:35-17:50	Eran Meshorer, The Hebrew University of Jerusalem, Israel NFIX, which is differentially methylated between modern and archaic humans, regulates vocalization in mice
17:50-18:05	Yonatan Stelzer, Weizmann Institute of Science, Israel Modeling mouse gastrulation at single embryo and single-cell resolution
18:05-18:20	Nissim Benvenisty, The Hebrew University of Jerusalem, Israel Defining Human Pluripotency and Gastrulation Utilizing Genome Wide Screening in Haploid Embryonic Stem Cells
18:20-18:35	Break
18:20-18:35
18:35-19:20	ISTT Prize Presentation and Lecture- sponsored by Genoway
18:35-18:45	Wojtek Auerbach ISTT Prize Presentation
18:45-19:20	ALEXANDRA JOYNER (ISTT Prize Recipient), Sloan Kettering, USA Genetic exploration of neural stem cell self-renewal and plasticity
19:20-20:20	Social hour, chat with ISTT Prize winner, breakout social rooms
19:20-20:20

Tuesday, October 27
Time	Session/Lecture info
15:00-16:00	Session 3A and 3B: CONCURRENT SESSIONS 3A: LARGE ANIMAL TRANSGENESIS 3B: NON-MAMMALIAN TRANSGENESIS
15:00-16:00
15:00-16:00	Session 3A: Large Animal Transgenesis Chair: Bruce Whitelaw
15:00-15:15	Jun Wu , UT Southwestern Medical Center, USA Derivation of intermediate pluripotent stem cells amenable to primordial germ cell specification.
15:15-15:30	Hui Yang , Chinese Academy of Sciences, China Interspecies blastocyst complementation generates functional rat cell-reconstituted forebrain in mice
15:30-15:45	Alison Van Eenennaam , UC Davis, USA Agricultural animal transgenesis for food applications
15:45-16:00	Nathan Buzzell , LFB, USA Transgenic goats expressing high levels of recombinant Trastuzumab in milk over multiple generations
15:00-16:00	Session 3B: Non-mammalian Transgenesis Chair: Richard Behringer
15:00-15:15	Claude Desplan , New York University, USA Manipulating aging
15:15-15:30	Swathi Arur, MD Anderson Cancer Center, USA Transgenic and CRISPR analysis in C. elegans
15:30-15:45	Tessa Montague, Columbia University, USA The neural basis of cuttlefish camouflage
15:45-16:00	Tim Corbin, Stowers Institute, USA Development of methodologies for the generation of genetically modified snails, Pomacea canaliculatae (Gastropoda, Ampullariidae), a novel, non-mammalian research organism
16:00-16:15	Break
16:00-16:15
16:15-17:15	Session 4: Ethics discussion by panelists - Ethics of Gene Editing in Animals Chair: Lluis Montoliu
16:15-16:30	Lluis Montoliu, Centro Nacional de Biotecnologia (CNB),Spain Some ethical considerations of genome editing techniques for the generation of mutant mice
16:30-16:45	Kirk Leech , The European Animal Research Association Animal Research: Time to talk!
16:45-17:00	Andy Greenfield , MGU,Harwell,Oxford,UK Genome editing and farmed animals: ethical considerations
17:00-17:15	Ethics Discussion by Panelists Lecture
17:15-17:20	Break
17:15-17:20
17:20-18:20	Poster Session 1
17:20-18:20
18:20-19:00	SOCIAL HOUR, BREAKOUT SOCIAL ROOMS
18:20-19:00

Wednesday, October 28
Time	Session/Lecture info
15:00-16:00	ISTT General Assembly
15:00-16:00
16:00-16:15	Break
16:00-16:15
16:15-17:15	Session 5: Germ Cells, IPS and Trophoblast Cells Chair: Yonatan Stelzer
16:15-16:30	Nicolas Rivron, Austrian Academy of Science, Vienna Blastoids: modeling blastocyst development and implantation with stem cells.
16:30-16:45	Nitzan Gonen, Bar-Ilan University,Israel Testis formation in XX individuals resulting from novel pathogenic variants in Wilms' tumor 1 ( WT1) gene
16:45-17:00	Yossi Buganim, Hebrew University-Hadassah Medical School, Jerusalem, Israel Comparative Parallel Multi-Omics Analysis of Cell Undergoing Reprogramming to Pluripotent and Trophectoderm States
17:00-17:15	Q&A
17:15-17:50	ORBIS PICTUS Lecture- sponsored by the Czech Centre for Phenogenomics
17:15-17:50	ORBIS PICTUS Lecture ELIZABETH HILLMAN Visualizing in-vivo systems at the speed of life
17:50-18:00	Break
17:50-18:00
18:00-19:00	Poster Session 2
18:00-19:00
19:00-20:00	Session 6: Roundtable - Running a Transgenic Unit Chair: Peter Hohenstein
19:00-19:15	Ben Davies, Oxford University, UK Panelist
19:15-19:30	Lisbeth Ahm Hansen, Aarhus University, Denmark Panelist
19:30-19:45	Karen Brennan, Australian National University, Australia Panelist
19:45-20:00	Philip Damiani, Charles River, US Panelist
20:00-20:45	Social hour, breakout social rooms
20:00-20:45

Thursday, October 29
Time	Session/Lecture info
15:00-15:45	Session 7: 3Rs Chair: Branko Zevnik
15:00-15:15	Ivo Huijbers, Netherlands Cancer Institute,Netherlands Rapid generation of versatile cancer models with minimal breeding effort.
15:15-15:30	Sara Wells, MRC Harwell, UK Refining Phenotyping for Refined GA strains.
15:30-15:45	3Rs Prize -Lydia Teboul , MRC Harwell- sponsored by Janvier Labs Evolving the generation by genome editing of complex alleles and their validation
15:45-16:05	Young Investigator Award by Beno?t Kanzler This activity is supported by an independent medical education grant from Regeneron Pharmaceuticals, Inc.
15:45-16:05	Young Investigator Award - Hiromi Miura , Tokai University School of Medicine, Japan Development of targeted transgenic technologies before and after the CRISPR era.
16:05-16:20	Break
16:05-16:20
16:20-17:20	Session 8: Emerging Technologies Chair: Soren Warming
16:20-16:35	Kimberly Cooper, UC San Diego, USA CRISPR/Cas9-mediated super-Mendelian inheritance to facilitate study of genetically complex traits
16:35-16:50	Stephan Rosshart, University Medical Center Freiburg, Germany Born to be wild - utilizing the common link among mammals to create better translational research models
16:50-17:05	Daniel Schramek, Mount Sinai Hospital, Canada In vivo CRISPR technology to rapidly screen function of hundreds of genes within a single mouse
17:05-17:20	Jessica Woodley - IDT Sponsored talk, IDT, USA Improved methods for CRISPR HDR using Alt-R modified dsDNA donors and Alt-R HDR Enhancer V2
17:20-17:35	Break
17:20-17:35
17:35-18:05	Session 9: Animal models for COVID-19 Research Chair: Lauryl Nutter
17:35-17:50	Sander Herfst TBA
17:50-18:05	Benjamin tenOever, Icahn School of Medicine at Mount Sinai, USA Leveraging the host response to SARS-CoV-2 to generate
18:05-18:10	POSTER PRIZE AWARDS -Sponsored by Charles River by Christopher Dowdy
18:05-18:10
18:10-18:35	INTERACTIVE COFFEE BREAK - coffee rooms with discussion topics
18:10-18:35
18:35-19:10	EMBO KEYNOTE LECTURE
18:35-19:10	EMBO KEYNOTE LECTURE : JANET ROSSANT, Sick Kids, Canada Dynamics of early development- from embryos to stem cells
19:10-19:30	Concluding remarks, TT2022 presentation by Ernst-Martin Fuechtbauer, Peter Hohenstein
19:10-19:30

Coordinator & Accessibility Issues

Inbal Azoulay
inbal.azoulay@weizmann.ac.il

Program

All times in the program are listed as Israel Time

TT2020 Program

Monday, October 26

Coordinator & Accessibility Issues