EMBO Workshop on a:
Systems-Level View of Cytoskeletal Function
Multi-scale approaches for understanding cell architecture and dynamics

The cytoskeleton comprises a complex system of cytoplasmic fibrillar networks, and an associated set of regulatory elements and molecular motors. It interacts with all other cellular systems, providing a robust yet dynamic structural scaffold that determines cell shape, and affects cell adhesion and motility, intracellular trafficking, and the process of cell division. The cytoskeleton plays a pivotal role in the response of cells to numerous external stimuli, including the micro-topographic and mechanical properties of the surrounding microenvironment.

Development of systems biology approaches for studies of complex cellular phenomena associated with the cytoskeleton will provide new, powerful tools for investigating novel functions of the cytoskeletal system. In particular, the recent development of systems microscopy, using quantitative data from light microscopy for systems biology analyses and modeling, appears particularly well suited to research into the cytoskeleton. At the same time, the emerging systems microscopy field will benefit from a deeper understanding of the upcoming needs of cell biologists, in order to develop the most useful systems microscopy tools and methods for the future. 

Our aim with this meeting is to spark active exchanges and interactions between the systems biology/systems microscopy communities, and those researching the cytoskeleton. 

Program and Organizing Committees:

Alexander Bershadsky, Israel (Co-Chair)
Benjamin Geiger, Israel (Co-Chair)
Christophe Ampe, Belgium
Leah Gheber, Israel
Arnon Henn, Israel
Eran Perlson, Israel
Staffan Stromblad, Sweden