SISB2023 Program

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Tuesday, February 28
Time	Session/Lecture info
08:15-09:15	Registration& Welcome Notes
08:15-09:00	Registration and Coffee
09:00-09:15	Welcome Notes
09:15-12:10	CBASS
09:15-09:45	Philip Kranzusch, Harvard Medical School Evolution and evasion of antiviral immunity
09:45-10:15	Aaron Whiteley, University of Colorado Bacterial cGAS-like enzymes in phage defense
10:15-10:50	Coffee Break
10:50-11:20	Kevin Corbett, UCSD A bacterial E1-E2 fusion protein primes antiviral signaling in Type II CBASS systems
11:20-11:50	Malcolm White, University of St Andrews Cyclic nucleotide based antiviral defence: TIRs before bedtime
11:50-12:10	Erin Huiting, University of California San Francisco Bacteriophages inhibit and evade cGAS-like immune function in bacteria
12:10-14:00	Lunch
12:10-14:00
14:00-15:10	CBASS and other Signaling systems
14:00-14:30	Nitzan Tal, Weizmann Institute of Science TBD
14:30-14:50	Giedre Tamulaitiene, Vilnius University Functional and structural studies of Thoeris bacterial antiviral system
14:50-15:10	Sam Hobbs, Harvard Medical School Phage evasion of cyclic nucleotide-based immunity
15:10-15:50	Coffee Break
15:10-15:50
15:50-17:30	New systems
15:50-16:20	EMBO Young Investigator Lecture: David Bikard, Pasteur Institute Defense against the inactivation of defense systems by phages
16:20-16:50	Asma Hatoum, University of Illinois Anti-phage immune systems in staphylococci
16:50-17:10	Jack Bravo, University of Texas Structural insights into anti-phage targeting DISARM systems
17:10-17:30	Avigdor Eldar, Tel-Aviv University Arbitrium communication controls phage life-cycle through modulation of a bacterial anti-phage defense system
17:30-21:00	Reception & Posters
17:30-21:00

Wednesday, March 1
Time	Session/Lecture info
09:00-12:00	Evolution and ecology
09:00-09:30	Aude Bernheim, INSERM Conservation of anti-viral immunity across domains of life
09:30-10:00	Eugene Koonin, NIH Guns for hire: evolutionary entanglement between mobile genetic elements and defense systems
10:00-10:40	Coffee Break
10:40-11:10	Martin Polz, University of Vienna TBD
11:10-11:40	Melanie Blokesch, EPFL Pathogenicity islands of Vibrio cholerae turning into defense islands
11:40-12:00	Avigail Stokar Avihail, Weizmann Institute of Science Discovery of phage determinants that confer sensitivity to bacterial immune systems
12:00-15:00	Lunch & Posters
12:00-15:00
15:00-16:00	Evolution and ecology
15:00-15:30	Aravind Iyer, NIH Immunity, cell death and inclusive fitness in the evolution of organizational complexity
15:30-16:00	Sigal Ben Yehuda, Hebrew University of Jerusalem Mechanisms of bacterial tolerance response to phages
16:00-16:30	Coffee Break
16:00-16:30
16:30-17:30	Systematic approaches for studying defense
16:30-16:50	David Burstein, Tel Aviv University Deciphering microbial gene function using natural language processing
16:50-17:10	Alexander Harms, ETH Zurich No need to catch 'em all: Using a bacteriophage reference collection to study bacterial immunity systems
17:10-17:30	Nitzan aframian, Tel Aviv University Defense system expression controls a trade-off between protection range and autoimmunity
17:30-23:00	Free evening (busses to Tel Aviv)
17:30-23:00

Thursday, March 2
Time	Session/Lecture info
09:00-12:20	New systems
09:00-09:30	Joe Bondy Denomy, UCSF Anti-phage immunity in Pseudomonas aeruginosa
09:30-10:00	Julia Frunzke, Forschungszentrum Jülich Antiphage properties of aminoglycoside antibiotics
10:00-10:20	Tanita Wein, Weizmann Institute of Science Ancient origins of inflammatory cell death in bacterial immune systems
10:20-11:00	Coffee Break
11:00-11:30	Karen Maxwell, University of Toronto Prophage encoded anti-phage defences
11:30-12:00	Daan Swarts, Wageningen University The diverse functions and mechanisms of prokaryotic Argonaute proteins
12:00-12:20	Emily Kibby, University of Colorado Bacterial NLR-related proteins protect against phage
12:20-14:30	Lunch
12:20-14:30
14:30-17:30	New systems
14:30-14:50	Federico Corona, European Molecular Biology Laboratory (EMBL), Heidelberg Phages have evolved myriads of ways to circumvent bacterial retrons
14:50-15:10	Alice Maestri, University of Exeter Maestri is a novel bacterial innate immune system that synergistically interacts with CRISPR-Cas to protect against phage carrying anti-CRISPR counter-defence genes
15:10-15:40	Luuk Loeff, University of Zurich Structure and function of the Shedu prokaryotic immune system
15:40-16:00	Stan Brouns, Delft University of Technology Accumulation of defense systems drives panphage resistance in Pseudomonas aeruginosa
16:00-16:40	Coffee Break
16:40-17:00	Helena Shomar, INSERM Functional and Evolutionary analysis of Viperins across domains of life
17:00-17:30	Rotem Sorek, Weizmann Institute of Science New insights into defense and anti defense mechanisms
17:30-18:00	Conference summary
17:30-18:00
18:00-23:00	Party!
18:00-23:00

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Registration

Deadline for registration
January 10th , 2023

Deadline for abstract submission
January 10th , 2023

ORGANIZERS

Rotem Sorek
Weizmann Institute of Science
Aude Bernheim
INSERM, Paris France
Philip Kranzusch
Harvard Medical School

Program

SISB2023 Program

Tuesday, February 28

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ORGANIZERS

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